WebCARB-X accelerates global antibacterial innovation by supporting the development of new antibiotics and other life-saving products to combat the most dangerous drug-resistant bacteria. Our portfolio represents the world’s most scientifically diverse, early development pipeline of new antibiotics, vaccines, rapid diagnostics, and other ... WebThe evolution of drug resistance is facilitated by a number of factors, including increasing use of antibiotics and antimalarials; insufficient controls on drug prescribing; inadequate compliance with treatment regimens; …
Towards the sustainable discovery and development of …
Web19 ago 2024 · Several global health organizations and public–private partnerships (PPPs), including the Global Antibiotic Research and Development Partnership (GARDP), … WebTo address antimicrobial drug resistance, the EU-funded ′Novel approaches to bacterial target identification, validation and inhibition′ (NABATIVI) project was initiated. … tlsny dividend history
Collateral sensitivity profiling in drug-resistant Escherichia coli ...
Web18 nov 2024 · For most gram-negative bacterial species–antimicrobial group combinations, changes in resistance percentages between 2015 and 2024 were moderate, and resistance remained at previously reported high levels. For S. aureus, the decline in the percentage of meticillin-resistant (i.e. MRSA) isolates reported in previous years continued in 2024. WebScientists from IMI’s ENABLE project have found a new mechanism to target drug-resistant bacteria, opening up a promising new pathway for further research. The mechanism involves DNA gyrase, a well-known enzyme that is a target of already existing antibiotics. ENABLE scientists found a new way to inhibit this enzyme and kill drug … Web19 ago 2024 · An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to the ... tlso and lso