WebFeb 15, 2024 · Additionally, we highlight the major protein constituents that drive mitochondrial fission and the role of connections with the endoplasmic reticulum in establishing sites of membrane division. Collectively, we review decades of research that worked to define the molecular framework of mitochondrial fission. ... Proteins in the … WebDynamin, best studied for its role in clathrin-mediated endocytosis, is the prototypical member of a family of multidomain GTPases involved in fission and remodeling of …
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WebDynamin-2 is a ubiquitously expressed mechano-GTPase involved in different stages of the secretory pathway. Its most well-known function relates to the scission of nascent vesicles from the plasma membrane during endocytosis; however, it also participates in the formation of new vesicles from the Golgi network, vesicle trafficking, fusion processes … WebJan 11, 2012 · Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in membrane remodelling, has a critical role … containerland hamburg
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WebPurified dynamin readily self-assembles into rings or spirals. This striking structural property supports the hypothesis that dynamin wraps around the necks of budding vesicles where it plays a key role in membrane fission. The focus of this review is on the relationship … WebPrior data suggested that both membrane fission events of sporulation involve the SpoIIIE DNA translocase. SpoIIIE is required for cytoplasmic compartmentalization of the two … WebOct 1, 2009 · Alternatively, the release of dynamin from the membrane following constriction of the bud neck might facilitate fission of the lipid tube (Bashkirov et al., 2008). Furthermore, it has been proposed that actin dynamics could be involved in the fission and release of budding vesicles ( Itoh et al., 2005 ; Shin et al., 2008 ). effective pr strategies