Phospho stat6
WebJun 19, 2024 · Its agonist pioglitazone suppressed phospho-STAT6, while its antagonist T0070907 successfully reversed the inhibition of phospho-STAT6 expression and IgE secretion by PGE 1-alcohol. Meanwhile, in vivo asthma model, the PPARγ antagonist T0070907 was found to boost serum IgE and OVA-specific IgE levels in OVA-induced mice … WebApr 11, 2024 · We have observed that STAT6 was phosphorylated at Y641 and serine. Tyrosine phosphorylation is independent of JNK-1, while serine phosphorylation is dependent on the aforementioned kinase. By using chromatin immunoprecipitation assays, STAT-6 and JNK-1 were detected in some promoters but not in others.
Phospho stat6
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WebSTAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c. Specifications Show More WebHuman STAT6 has three isoforms; the molecular weights are 94, 82 and 74kD. The immunogen (phosphorylated peptide) is shared by these three isoforms. This antibody …
WebBlue Laser (488 nm) Application Notes. Human STAT6 has three isoforms; the molecular weights are 94, 82 and 74kD. The immunogen (phosphorylated peptide) is shared by these three isoforms. This antibody recognizes STAT6 Phospho (Tyr641) in all three isoforms. The predominant band detected is at 94 kD. Clone A15137E does not react with mouse.
WebBased on our data, it would be critical to confirm that neurons expressing IL-4R possess all the necessary components of the IL-4 signaling pathway; for example, phospho-STAT6 … WebBioTNT是一家专业提供生命科学分子生物学、蛋白质组学、免疫学等相关产品和服务的生物技术服务公司，包括抗体、蛋白、多肽、ELISA、生物芯片、Real Time PCR等等。BioTNT的仪器，试剂耗材和服务帮助研究人员提高科学研究能力，推动新的研究和开发，以便不断地改善人类的生活。
WebMay 18, 2024 · It is also noteworthy that the upregulation of pSTAT6 MFI was found to be IL-4 concentration dependent, with phosphorylation detected from 1 to 50 ng/mL (Sup. Fig. 5 a,b). However, regulation of...
WebRayBio® Phospho-Stat6 ELISA (Enzyme-Linked Immuno-sorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates. By determining phospho-Stat6 in your experimental model system, you can verify pathway activation in your cell lysates. ... grand hano resortWebFirst we verify that in a panel of cells in which different pathways have been induced, we see phosphorylation-specific staining only in the cells in which the specific pathway of interest … grand handzWebSTAT6 (phospho Y641) was immunoprecipitated from 0.35 mg of Daudi (Human Burkitt's lymphoma cell line) whole cell lysate treated with 100 ng/ml IL-4 for 15 minutes with ab188080 at 1/30 dilution. Western blot was performed from the immunoprecipitate using ab188080 at 1/1000 dilution. grandhanthar hospital in yangonWebApr 21, 2015 · Catalog Number: I was using the phospho-STAT6 antibody to determine if the IL-13 I purchased was causing activation of the JAK/STAT pathway in primary epithelial cells. This is a good antibody to detect the Tyr641 phosphorylated form of STAT6. I have not tried other antibodies for STAT6 but you don't really need to if you start with this one. chinese delivery stafford vaWebThis Sandwich ELISA kit is an in vitro enzyme-linked immunosorbent assay for the measurement of human phospho-STAT6 and total STAT6. An anti-pan STAT6 antibody has been coated onto a 96-well plate. Samples are pipetted into the wells and STAT6 present in a sample is bound to the wells by the immobilized antibody and the wells are washed. In ... chinese delivery spring txWebSTAT6 is a member of the signal transducer and activator of transcription (STAT) family, activating gene expression in response to IL-4 and IL-13 stimulation. Upon cytokine … grand haras playmobilWebThe FastScan™ Phospho-Stat6 (Tyr641) ELISA Kit is a sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of Stat6 when phosphorylated at Tyr641. To perform the assay, sample is incubated with a capture antibody conjugated with a proprietary tag and a second detection antibody linked to HRP, … chinese delivery spring lake nc